Generative Energy Episode Five: Energy and Structure (Respiration vs. Fermentation and Coherence vs. Incoherence) — The Danny Roddy Weblog

Generative Energy Episode Five: Energy and Structure (Respiration vs. Fermentation and Coherence vs. Incoherence) — The Danny Roddy Weblog.

Danny Roddy talks with me about respiration from the perspective of Ray Peat and Gilbert Ling, as well as talking about a dynamic liquid crystalline view of biology as found in Mae-Wan Ho’s work.

William Blake and other biopsychic visionaries: Imagination, energy, and alchemy.

“Art is the tree of life. Science is the tree of death.”

 “Energy is the only life, and is from the Body and Reason is the Bound or outward circumference of Energy.”

“Energy is eternal delight.”

“What is the life of Man but Art and Science?”

“The imagination is not a state: it is the human existence itself.”

 

“Truth can never be told so as to be understood and not be believed.”

-William Blake

 Self-Portrait-of-William-Blake

The imagination is typically seen as a sort of abstract fuzzy faint voluntary delusion generating faculty, however not all have seen the imagination in such terms, William Blake saw imagination as the defining human quality. Blake appeared to see Life as limitless magickal[666](and what is the imagination if not magical) innovation, imagination as an active conscious expression of living energy.

Blake saw reason and “science”, at least in their reductionist expression, as in opposition to the full expression of humanity, they were for Blake an expression of insanity, and I agree. Whilst psychosis and various forms of schizoid behaviour are typically considered forms of highly irrational behaviour, I think it might be more accurate to view such states as magnifications or intensifications of a particular kind of reasoning, one that has become divorced from intuition, and centred biopsychic perception and instead lost itself in a labyrinth of self-referential reasoning, a fairly common manifestation of this sort of madness is when an individual ceases to trust in their own will and creative choice, and instead attempts to “decode reality” through obsessively interpreting everything around them as sorts of omens or signs, from which to determine appropriate behaviour (usually resulting in highly inappropriate behaviour, often hilariously so, sometimes tragically), seemingly unable to trust in their own guidance systems. I think this is especially common in highly authoritarian cultures, as individuals are consistently taught that appropriate behaviour must come from an authority.

 

“The man reared under and bound by authority has no knowledge of the natural law of self-regulation; he has no confidence in himself. He is afraid of his sexuality because he has never learned to live naturally. Thus he declines all responsibility for his acts and decisions and demands direction and guidance.”

-Wilhelm Reich

 

The world for people caught up in such a state becomes both a sort of puzzle to decode, and once “decoded” a set of instructions to follow. Whilst such states are obviously transient, being simply a state of profound confusion, the current psychiatric medical model claims that individuals experiencing such states are “chemically unbalanced” as a result of… “genes”. The victim of this psychiatric bullying is told essentially that they are fundamentally defective, any attempts they might make to understand and deal with the situation themself are essentially useless, they must take the prescribed drugs (typically metabolic toxins), if the victim attempts to question the diagnosis and / or prescription, this is considered further compounding evidence of their “genetic” sickness (the technical terminology is that the patient “lacks insight”), the psychiatrist is after all an authority, and current medical psychiatry clearly understands the nature and infinite nuances of human consciousness (just in case you weren’t sure this is sarcasm). I think this forced drugging of psychiatric patients is a profoundly violent and dehumanising act. The psychiatric prison is a distillation of everything that is wrong with authoritarian culture. Psychiatry like the “war on drugs” appears to be  an attempt to limit free consciousness. Some psychiatrists appear to be playing out narcissistic power fantasies, having zero empathy for their patients/victims, for a “patient” questioning the authority and opinions of these shrinks is generally a bad idea.

The approach to life, outlined in the above description of a psychotic state, has a lot in common with the attitudes of some scientists, for example Rene Descartes appears to have taken such a view, seeing the world as a great machine operating according to fixed laws,

“Descartes had a dream and in this dream an angel appeared to him, this is documented by his own hand, and the angel said to Descartes, “The conquest of nature is to be achieved through measure and number.” And that revelation lay the basis for modern science.”

Within this mechanical world bound by measure and number the human soul interfaces with a mechanical body through the pineal gland alone, this dualism is opposed to Blake’s view, “Man has no Body distinct from his Soul”. Exactly how Blake would have seen Descartes “angel” is unknown, but I think Blake might have seen this “angel” as a representative of Urizen. Descartes was forced into this dualistic conception of body and soul because he viewed life as mechanical, the world was made of lumps of dead matter interacting through clunky mechanism, and at least realized that explaining the subtelties of mental experience through mechanism was no easy task, apparently today some “scientists”, have gone further than Descartes in such mechanical madness suggesting that,

“We are survival machines – robot vehicles blindly programmed to preserve the selfish molecules known as genes. This is a truth which still fills me with astonishment.”

-Richard Dawkins: The Selfish Gene

I’m also astonished, that someone can believe something like this, its absurd and explains less than nothing.

Dawkins is apparently unsure of whether animals are conscious, and has stated that consciousness (even human) may be an illusion. Again these insane views can be traced back to Descartes and those like him who denied that animals had souls seeing them as beast-machines, who did not really experience pain, the animals apparent experience of pain, a complex illusion, yelps or screams and attempts to avoid the source of injury, merely mechanistic reflexes emitted by an automaton. Blake found this view monstrous, his views on the “ensoulment” of animals are clear.

“A horse misused upon the road

Calls to heaven for human blood.

Each outcry of the hunted hare

A fibre from the brain does tear.

 

A skylark wounded in the wing,

A cherubim does cease to sing.

The game-cock clipt and arm’d for fight

Does the rising sun affright.”

-William Blake, Auguries of Innocence.

These “enlightened” scientists believe some fundamentally absurd things, all whilst claiming to be rational, though a very particular sort of rational, one that has chained reality in their own limited conceptions. As a result the “science” that has been engineered by these people is one that is dead, reflecting their own view of life back at them, justifying the moronic cruelties that are perpetrated in the name of “science”, animal experimentation and vivisection, justified because animals aren’t really conscious, just complex survival machines. This dead mechanical view of life and nature driven by random processes leads to our treating nature as lifeless, and in doing so we disrupt, sicken, and distort the web of Life that supports us. There is little evidence to support this mechanical view of life, which exists as an unquestioned dogma of contemporary science, derived to a large extent from “rational” deists like Descartes and Newton who viewed the Cosmos as a complicated clockwork automata created by a distant “divine watch maker.” This obsession with mechanical metaphor has been relatively constant, the absurdity of this view reaching its zenith in atheistic mechanists who believe in a clockwork universe comprised of teeny tiny, discrete, quantized, bits of dead unconscious matter, that some how jumbled together into amino acids that further jumbled together into solutions contained in sacks of water surrounded by oily membranes, these water sacks assembled into multicellular bio-machines, complexifying through a “biological” evolution driven by random mutations selected out by a crude mechanism “red in tooth and claw”, that eventually produced human beings, capable of producing art, music, painting, sculpture, architecture, and dance, this creativity some would have you believe is a product of a consciousness that is an illusory epiphenomenon. Furthermore this all takes place in vast, dead cosmos that was born once upon a time when nothing exploded (the Big Bang?!?), the deistic conception of the universe is bizarre, the reductionist view insane (“the limit test for credulity”), strangely such ideas are treated as reasonable.

“For approximately 500 years [science's] argument for its pre-eminence was that it could create beautiful toys: aircraft, railroads, global economies, television, spacecraft. But that is a fool’s argument for truth! I mean, that’s after all how a medicine show operates, you know: the juggler is so good, the medicine must be even better! This is not an entirely rational way to proceed.”

-Terrence McKenna

 Newton-WilliamBlake

This mechanical view of life is also a very convenient myth, historically (and still today) the pseudo Darwinian mechanical evolutionary model has appealed to ruling classes, seeking justification for their dominance. The genetic determinist paradigm being essentially a rebranding of eugenics. This myth supports the interests of corporatism, leading to vastly wasteful research into profitable disease treatments, not cures, a patient cured is a customer lost.

Evolution of both organisms and the biosphere is absolutely purposeful, and of course purpose requires intelligence, no purpose without mind or intention. To suggest that All that we see around us has come about by blind, random, chance, is well staggeringly stupid, a person does not achieve accomplishment of any sort through random chance, will, directionality is involved, choice.

For example, Ray Peat has not become Ray Peat through random events, he chooses purposefully to investigate, to examine possibilities, to search through the thoughts and work of others, to attend to his own perception and sensitivity, seeking for a coherent understanding of Life.

“Passively taking whatever you are given, by history and nature, is entropic; choosing intelligently from possible diets, selecting courses of action, will create pattern and reduce entropy.”

-Ray Peat

To suggest that humans have come about through random chance mutations seems insane, we are purposeful, and all those who have contributed in any way to what human civilisation we have, have consciously lived with purpose.

Purpose is negentropic / Kosmotropic, we see in this world, despite the monstrous stupidity, the ecological disasters and wars wrought by human ignorance, there is order, Kosmos, biological Life.

Further we see evidence that biology both organisms and the biosphere have qualitatively evolved becoming ever more complex, ever more, energetic, ever more conscious and aware.

Adults are generally more individuated than children, however this requires a sort of choice, an exploratory expansion into possibility, the general culture opposes this on multiple levels, the inevitability of distorting trauma seems almost inescapable, learned helplessness is ubiquitous and an individual’s free growth is frustrated through a  toxic culture that blinds people to their own potential.

To suggest that the Life we see around us has become what it is without purpose seems absurd, an absolute denial of reality, and yet this is the position that is treated as reasonable by mainstream science, praise be to Random Chance!

The mechanical model obviously contributes to the problems of psychiatry, beyond categorising individuals struggling to effectively orient themselves within a deranged antihuman culture as mysteriously “chemically imbalanced” and genetically defective, it also automatically discounts the possibility that some individuals may in fact have more finely tuned sensory capacities, if a person hears things or sees things that others don’t the assumption is that they are crazy, this problem is compounded by the distinct possibility that if someone was to find their sensory abilities very suddenly becoming more refined, and plunged into perceptions they had previously not experienced, their ability to orient themselves to these new perceptions might at first be a little shaky, like a child learning to walk, it seems likely that they might have a few falls as they learn to orient themselves to these new perceptual capacities.

 

“Indubitably, Magick is one of the subtlest and most difficult of the sciences and arts. There is more opportunity for errors of comprehension, judgement and practice than in any other branch of physics.”

-Aleister Crowley

William Blake claimed to see visions, and hear voices, at times finding these experiences disturbing, he eventually integrated them into his life and was enriched by them. The general consensus of many of his contemporaries was that Blake was charming, though quite mad.

Much of modern science is self-limiting, it has imposed false limits on reality, jumped to conclusions about the nature of Life that are groundless, based only on the dull preconceptions of limited minds that argue noisily for them, genetic determinism and the idea that consciousness is an epiphenomenon arising from electrically firing neurons, are perhaps the most problematic example of this. When people are taught that their identity is determined by genes, and that their consciousness is complicated illusion, that they are inconsequential, an accident adrift in cold dead Cosmos, a passive attitude is encouraged, this attitude renders them easily manageable on large scales, if life is dead mechanistic matter then why seek anything else other than meaningless entertainments, work, pay the bills, and if there’s any left over spend it on more vacuous junk.

“Reason, or the ratio of all we have already known, is not the same that it shall be when we know more.”

Blake was critical not only of reductionist science but conventional religion, which he saw as Life-denying curse, the body and sensual experience seen as sinful distractions, the material world for the religious was just a dead world created by “Old Nobodaddy aloft”, the idea of God as the distant Grand Architect, was for Blake madness, such an idea could not describe true Divinity but only a half mad demiurge, the limited and limiting, Urizen. These life-denying interpretations of religion have oddly enough formed the basis of the current secular reductionist tendencies in science.

These dualistic conceptions, that propose either a physical world created by a distant sky giant, with a vaporous metaphysical soul interacting with an earthen body through the pineal gland, or a world of dead matter, with consciousness as an illusory epiphenomenon have contributed to the gross stupidities that currently endanger all life on this planet.

If instead we were to imagine that consciousness was the fundamental property of Life, intrinsic to biology, how would this affect our approach to life? If all things that live are conscious surely that means that we share in this experience with them, if “worms and flies and ants are conscious and in the same situation as human beings, the bonds of sympathy and forgiveness are universal.”

I think it is possible that the greatest evidence for a living Kosmos is the sensitivity of the human nervous system, a sensitivity that simply cannot be explained by the mind numbingly stupid explanations of conventional biology reliant on nerves functioning through binary all or nothing signalling, mediated through the actions of mechanical “pumps” installed in fatty membranes. To believe that this model of nerve biology explains the exquisite sensitivity that we experience through our various senses, the vision of the iridescent peacock’s tail, the deeply nuanced sense of hearing that allows for the experience and creation of music, our senses of smell taste, touch and proprioception, to suggest that our living experience is a product of digital nerve function is insane, a denial of vibrant Living reality.

Further if we accept that consciousness is intrinsic to biology, the sensitivity of organisms being convincing evidence that this is so, the question then becomes where did this consciousness come from? Is it possible that matter is consciousness, biology being this matter becoming more conscious / energetic, waking up to its latent potential, exploring its possibilities, evolving itself? It would also follow that the Universe itself is conscious, biological and biophilic.

“The psyche cannot be totally different from matter for how otherwise could it move matter? And matter cannot be alien to the psyche, or else how could matter produce psyche? Psyche and matter exist in the same world and each partakes of the other, otherwise any reciprocal action would be impossible. If research could advance far enough, therefore, we would arrive at an ultimate agreement between physical and psychological concepts.”

-Carl Jung

 

We don’t know what “matter” ultimately is, the sensitivity demonstrated to be intrinsic to matter by JC Bose, who found that metals subjected to various mechanical, thermal, chemical, and electrical stimuli demonstrated electrical excitatory and fatigue responses similar to living biological material1, suggests that it may be meaningless to attempt to split these concepts, matter and mind.

The evidence for the spontaneous formation of biological life, found by various individuals including Sidney Fox2 and Wilhelm Reich, would suggest that given the right circumstances and stimulus “non-living matter” can somehow learn to reconfigure itself into living forms, suggesting that a primitive consciousness has awoken.

“The dualistic conception of matter as distinct from energy and consciousness is a constrictive illusion put in place by the forces of empire, and the living reality would be freed from the inert husks of the wrongly conceived natural world”.

-Ray Peat.

This could be considered a materialistic proposition, however one that understands that “matter” is something in process, and if so the dream of the Alchemists may be a real  possibility, the “spiritualization” of  “matter”,  making “matter” ever more energetic and ever more consciousness, and with this an increase in the various attributes of consciousness; simplicity, play, purpose, compassion, creativity, insight, and grace. Ever greater freedom, ever more Life.

If consciousness is understood to be the fundamental quality of Life, inseparable from biology, then we are no longer imaged as victims of a genetic lottery adrift in a cold dead universe, but instead active creative participants in the unfolding and expression of both our own psychobiology and that of the living Cosmos that nurtures and supports us.

“The joy of life consists in the exercise of one’s energies, continual growth, constant change, the enjoyment of every new experience. To stop means simply to die. The eternal mistake of mankind is to set up an attainable ideal.”

-Aleister Crowley

Consciousness clearly interacts with biology in a deeply intimate way, anyone who has observed the relationship between breath and psycho-emotional state must have realised this. Multiple studies show that conscious awareness is capable of generating biological changes, increasing the convolutions and surface area of the cerebral cortex, optimizing metabolism, changing brain wave patterns, increasing or decreasing healing, the limits of conscious biopsychic modification are unknown, this is a vast and for the most part unexplored territory, the horizon cannot be seen.

Cracking open the Mundane Shell

Cracking open the Mundane Shell

“We’re supposed to keep evolving, evolution did not end with us growing opposable thumbs.”

-Bill Hicks

 

“God sleeps in stone, breathes in plants, dreams in animals, and awakens in man.”

-Hindu proverb.

 

“He whose face gives no light, shall never become a star.”

-William Blake


[666] “Magick is the Science and Art of causing Change to occur in conformity with Will.”

1 Bose found that metals and living tissues (plant and animal) were all benumbed by cold, intoxicated by alcohol, wearied by excessive work, stupified by anaesthetics, excited by electric currents, stung by physical blows and killed by poison. All exhibit essentially the same phenomena of fatigue and depression, together with possibilities of recovery and of exaltation, as well as the possibility of permanent irresponsiveness, death.

2 “Fox put nearly dry amino acids onto hot volcanic rocks, and when he added a little water, the amino acids polymerized spontaneously, and nonrandomly, into peptide chains; when these were put into water, they spontaneously formed microspheres, that looked like, and behaved very much like, bacteria. Fox saw his work as a validation of the principle that nature itself created higher order spontaneously.”  In Fox’s production of the proteinoid microspheres, the ordered growth is a consequence of the properties of the substance in a permissive environment. The order is not imposed from the outside onto passive matter.

Terence McKenna: psychonaut

“If then you do not make yourself equal to God, you cannot apprehend God; for like is known by like.

Leap clear of all that is corporeal, and make yourself grown to a like expanse with that greatness which is beyond all measure; rise above all time and become eternal; then you will apprehend God. Think that for you too nothing is impossible; deem that you too are immortal, and that you are able to grasp all things in your thought, to know every craft and science; find your home in the haunts of every living creature; make yourself higher than all heights and lower than all depths; bring together in yourself all opposites of quality, heat and cold, dryness and fluidity; think that you are everywhere at once, on land, at sea, in heaven; think that you are not yet begotten, that you are in the womb, that you are young, that you are old, that you have died, that you are in the world beyond the grave; grasp in your thought all of this at once, all times and places, all substances and qualities and magnitudes together; then you can apprehend God.

But if you shut up your soul in your body, and abase yourself, and say “I know nothing, I can do nothing; I am afraid of earth and sea, I cannot mount to heaven; I know not what I was, nor what I shall be,” then what have you to do with God?”

-Hermes Trismegistus

“But to the Eyes of the Man of Imagination, Nature is Imagination itself. As a man is, So he Sees. As the Eye is formed, such are its Powers.”

-William Blake

“I must create a system. or be enslav’d by another mans; I will not reason and compare: my business is to create”

-William Blake

I think Terence is wrong about needing to smash atoms to understand them, but making unusual choices that are outside of established cultural boundaries is a valid psychedelic technique.

Our brain grows into our culture, and the culture lives in our nervous system.

-Ray Peat  (Academic authoritarians, language, metaphor, animals, and science)

“Adaptation to one’s environment makes for a sort of survival; but after all, the supreme victory is only won by those who prove themselves of so much hardier stuff than the rest that no power on earth is able to destroy them. The people who have really made history are the martyrs.”
-Aleister Crowley

For more Terence McKenna check out Lorenzo’s Psychedelic Salon:  http://www.matrixmasters.net/salon/

Consciousness, morphogenetic fields, regeneration, cancer and respiration (in context).

axolotl

The dogmatists insist that life must be explained in terms of physics as they understand it, and it happens that their “physics” is nothing but a doctrinal relic kept in place to justify their conceptions of biology.

-Ray Peat

So I’ve blogged previously about a lot of this, but I think it would be useful to explore these ideas in more detail, as these areas are key to understanding the nature of biological life, as well as presenting solutions to some of the medical problems that the corporatocracy is unwilling to intelligently address.

The conventional view is that an organism’s form is an expression of a “genetic program”, that cancer is produced by rogue clonal genetic mutants, and that organisms capable of regeneration possess magical regeneration “genes” that trigger unconscious regenerative programs. There is good evidence that this biomechanical model is wrong. If an alternative view is adopted, one that examines the issues of morphogenesis, cancer and regeneration in holistic bio-energetic terms then the total organismic environment, respiratory intensity, and consciousness appear to come to the fore as the key issues in understanding these subjects.

In order to think about and understand morphogenesis, cancer and regeneration we need to think in terms of fields or at least field like effects, the current medical culture mired in reductionism neglects such ideas, but developmental fields of various sorts clearly have a functional reality. The essential quality of a field model is holism, a point is influenced by the larger whole in which it finds itself.

Epigenetic factors play key roles in pattern formation, these include, chemical gradients, electrical gradients, environmental stimuli, cell-cell contacts, all of these factors have in common metabolic processes, including both generation by respiratory processes and the ability to modulate respiration.

These morphogenetic fields are I think manifested by consciousness. Consciousness, whether or not it can be explained, must be included in a holistic biology, as it is the fundamental attribute of biology, the sensitivity of organisms is consciousness in action, to exclude consciousness as a factor in biology is insanity. An organism is a pattern unfolding in time, oriented by consciousness.

What is metabolism? What is respiration? Understanding these concepts is critical to understanding the nature of life, the way these concepts are often understood in isolation from the organism as a whole can leave people with distorted ideas as to what metabolism and respiration actually are, at least that is the impression I get when I speak to some people about these ideas. The metabolic processes often appear to be understood as some kind of mechanical combustion engine, that burns up fuel like car engine, and that the best way to increase metabolism is engage in mindless exercise.

One of the criticisms often directed at Ray Peat is that he seems to think thyroid is the solution to everything, and hence he must be a quack, because thinking about the possibility of elegant panaceas is unscientific. If you believe that metabolism and life occur through the actions of ion and proton pumps installed in lipid bilayer membranes, then a focus on metabolism might seem as strange as suggesting that you fix a car’s flat tire by installing a new spark plug. So how could supporting thyroid function and improving metabolism correct, say, an arthritic condition?

The current mechanical model of biology, obscures the centrality of metabolism in the maintenance of the organism. This mechanical model leads people to suggest that lowering of metabolism is optimal if you want to achieve longevity, after all continual use of a car will lead to a more rapid breakdown of the parts, thankfully we are not machines.

If a different view of the Life process is taken, wherein Life is seen as a self-organizing dissipative structure, somewhat like a Belousov-Zhabotinsky reaction or a cyclone. In such a model, coherent energy flow (metabolism) becomes on obvious focal point.

Energy and structure

Structure is generated by the energetic “whirlwind” of the respiratory process, distortions/interferences in respiration inevitably lead to structural distortions of one sort or another. However if interfering with respiration distorts structure, then supporting respiration will heal the organism.

 

“The intensity of oxidative metabolism is the basic factor that permits continuing coordination of activity, and the harmonious renewal of all the components of the organism.”

-Ray Peat

When the importance of respiration in healing and morphogenesis is examined it seems clear that the appearance of physicality is superficial, and an energetic reality emerges. Take for example the “injury potential”, where injured tissue will be electrically negative relative to uninjured, this electronic excitation might be more accurately seen as an incoherent discharge, which arises when the coherent energetic flow of the living state is disrupted. As Ray Peat has pointed out the so-called “membrane potential” is just another “injury potential”, the “membrane potential” is measured through piercing the cell with a micro-electrode, and because the cell is injured by this procedure its energetic structure is disrupted, and discharges creating the impression that the inside of the cell is “negative” in comparison to the outside. A sort of energetic decay can be seen, in simple injury, as well as other conditions demonstrating increased “reductive” stress, the “electrons” arise from the energetic disruption. Instead in the uninjured coherent living state the “electrons” are in a state of delocalized charging centripetal flow, manifesting in what is conventionally referred to as a more oxidized state. The nuclear theory of the atom seems questionable. The over reduced state of injury, cancer, as well as the active / dead state of Ling’s AI hypothesis could all be viewed as various degrees of energetic discharge and departure from the charged electronically desaturated living state. Agents such as ATP and CO2 which in Ling’s terminology are electron withdrawing cardinal adsorbents act to restore charge and coherent energy flow.

A thyroid supplement is one possible means of supporting respiratory intensity in an environment that contains many anti-respiratory factors (xeno-estrogens, fluoride, radiation, carrageenan, PUFA, etc).

The problems of cancer and regeneration or the lack of regeneration, are related problems, cancer is an excess of new tissue, which fails to integrate into the organism as a whole. Organisms capable of regeneration are remarkably resistant to cancer, even artificial attempts at inducing cancer in such animals are difficult, tissues exposed to carcinogens normalise rapidly, when tumors are transplanted onto amputated limb stumps of newts they are typically assimilated into a new limb (Oviedo and Beane 2009). This observation seems unremarkable, but if the mechanistic genetic reductionism of the scientific “orthodoxy” is correct the opposite might be expected, organisms whose cells are phenotypically labile, capable of relatively easy de-differention, and swift proliferation, might be expected to be prone to spontaneous cancer generation. However a model that works with a “morphogenetic” field would expect that regeneration and cancer should be inversely related, the field strength required for regeneration would also render cancer unlikely.

The regenerative blastema, a mass of undifferentiated cells, that forms from previously differentiated cells as part of the early regenerative process, shares features of cancer, and such similarities have led to theories that cancer represents an attempt at healing that somehow fails to be controlled by the normal processes of morphostasis.

Embryos also demonstrate significant resistance to cancer, human metastatic melanoma cells transplanted into chick embryos differentiate and function normally within the host (Kulesa et al. 2006). Malignant mouse teratocarcinoma cells were injected into mouse blastocysts (a pre-embyronic developmental form), the tumour cells differentiated into multiple normally functioning tissues, including immune cells, liver cells, and sperm cells, the mice produced were genetic chimeras capable of passing on genetic material from the tumour cells to their progeny, the same teratocarcinoma cells injected subcutaneously in mice form cancers (Mintz and Illmensee 1975). Gestating organisms also display significant regenerative abilities, and scar free healing (Redd et al. 2004).

Given a natural tendency of cells to multiply, the interesting thing about regenerative healing is the question of why the new growth of tissue sometimes differentiates to fit appropriately into its surroundings, but sometimes fails to differentiate, becoming a tumor.

-Ray Peat.

There is now good evidence that the old idea that cancer is tissue that has escaped from the organising pattern of the individuation field is correct, the differentiation of cells is dependent on environmental signals, isolated cells are known to lose most functional differentiation when separated and placed in traditional cell cultures. Breast cancer cells implanted into in vitro tissue matrices containing collagen, fibroblasts, and basement membrane demonstrated near complete phenotype reversion, becoming more differentiated (Krause et al. 2010). The ability of the larger tissue environment to normalise cancer cells clearly demonstrates that cancer is a problem of organisational signalling.

This organizing field can be seen in regeneration and morphogenesis, in study where developmental defects were induced in tadpoles, by manipulating the embryonic voltage gradients that guide craniofacial patterning, displacing jaws and branchial arches, subsequent development was able to adjust and reshape to correct these perturbations (Vandenberg et al. 2012). Clearly morphogenesis is a dynamic holistic patterning process.

I think it is likely that morphogenesis and regeneration are examples of intelligence in the organism, they are guided by consciousness, no doubt this stinks of vitalism. The typical explanations for regeneration and morphogenesis rely on cascades of molecular signaling read out from genetic code, but this sort of reductionism fails to explain anything meaningful.

In a number of studies it has been shown that denervation results in the loss of regenerative capacity, although regeneration continues as normal if the nerve regenerates (Singer 1952). A study found that higher nerve quantity relative to non-nerve tissue was positively associated with regeneration in frogs, small young froglets, with a higher quantity of innervation were capable of regeneration, larger froglets and adults, with about half the innervation quantity of their smaller counterparts were completely devoid of regenerative capacity, however if their innervation was increased by deviating sciatic nerve bundles to the forelimb stump, almost all limbs which were usually non-regenerative with normal innervation demonstrated at least some regeneration (Kurabuchi 1992). The role of the nervous system in regeneration is further supported by observations that the regenerating limbs of newts, have a greater quantity of innervation (axoplasm of nerve per area of limb cross-section) than the normally non-regenerating limb of adult frogs. These studies might explain to some extent the increased regenerative capacity of young animals including human children who are recorded as having have regenerated finger tips, when the wound has not been stitched up by medical authorities. Young animals have a proportionally greater degree of nerve tissue.

If innervation (nerve supply) is involved in regeneration and there is a relationship between regeneration and cancer, denervation should affect carcinogenesis, multiple studies suggest that it does. Rats subjected to subdiaphragmatic truncal vagotomy developed tumors and carcinoma of the gastric mucosa (Kaminishi et al. 1995), denervation of sensory nerves with capsaicin increased tumor metastases of the heart and lungs in mice (Erin et al. 2004). Denervation has other effects on tissue, causing increased excitability and muscle spasm, inducing atrophy in muscles, changes in vascularization including narrowing of the lumen of arterioles increased collagen deposition, and capillary necrosis (Carpenter and Karpati 1982, and Borisov et al. 2000), denervation increases mast cells (de Morais et al. 2008). Denervation also causes changes to mitochondria, decreasing the activity of respiratory enzymes including cytochrome oxidase, decreasing cardiolipin (Wicks and Hood 1991), in muscle tissue denervation reduces mitochondrial size, leads to changes in mitochondrial arrangements, with mitochondria becoming less organized (Miledi and Slater 1968).

Interestingly height in humans is positively associated with cancer, tall people get more cancer, it is possible the ratio of brain and nerve tissue to body size play a similar role here as it appears to with regenerative capacity (Green et al. 2011).

Given that nerve supply plays a clear role in morphostasis, promoting regeneration, differentiation, and inhibiting cancer, as well as exerting trophic effects preventing tissue atrophy, the suggestion that consciousness might be intimately involved in these processes does not seem unreasonable, unless there is an irrational adherence to an ideology that claims that consciousness is an illusionary ghost in the machine of biology. The idea that consciousness is involved in healing is supported by a study where the rate of healing was lower in individuals with poor anger control, these individuals also had higher cortisol levels when wounded (Gouin et al. 2008).

I think some studies showing that denervation increases lactate and reactive oxygen species (ROS) production (Karpati et al. 1979, and Muller et al. 2007), and a study showing that meditation decreased lactate (Perez-De-Albeniz and Holmes 2000) suggest that it is consciousness that centres the respiratory whirlwind, and that consciousness is capable of increasing the coherence of energy flow and cytoplasmic microstructure, evidenced in reduced plasma lactate.

There are studies (McCaig and Rajnicek 1991) demonstrating that nerves grow towards cathodes (negative polarity) this seems to suggest that the conscious organism senses the energetic discharge (negative polarity) produced by injury and that the nerves as potential regulators of the morphogenetic field grow towards it in an attempt at restoring coherence. Cancer cells have also been shown in one study to migrate towards cathodes (Yan et al. 2009), this might support the idea that cancer is in some way an attempt at healing. Robert Becker and others have studied the electrical properties of wounds and regenerating tissue, they have also succeeded in inducing incomplete regeneration in rats using implanted bimetallic electrogenic devices to simulate the electrical environment in the tissues of regenerative animals such as salamanders, the rats regenerated missing portions of the humeral shaft along with differentiated muscle tissue (Becker and Spadaro 1972).

Becker (1960), has also shown that the central nervous system appears to be intimately involved in the bioelectric fields generated by organisms, the spatial organization of the field correlated with the morphology of the central nervous system, areas of nerve cell aggregations in the central nervous system appear to serve as both sources and sinks of the potential, with transmission along major nerve trunks. Becker concluded that the dc bioelectric potential in organisms may be generated within and conducted by portions of the central nervous system. Borgens disagrees with Becker arguing that denervation was associated with increased current leaving the amputated limb (Borgens et al. 1979), I think there might be a way of reconciling this apparent contradiction, with the nervous system acting in some way to structure the total bioelectric field.

Interestingly the “immune system” also appears to play a role in regeneration, macrophage depletion of axolotls resulted in failure of limb regeneration, the wound closed over with extensive fibrosis, if macrophages were restored and the stump re-cut regeneration occurred (Godwin et al. 2013). I think this study supports the idea that the “immune system” might more accurately be described as a morphostatic “clean up the mess” system as Jamie Cunliffe has proposed (http://www.morphostasis.org.uk/). A new perspective on the “immune system” might lead to some rational thinking about and solutions to the so-called “auto-immune” diseases.

Predictably (the lymphoid organs are innervated by sympathetic nerves) denervation also affects immune function, reducing generation of cytotoxic T-lymphocytes and mobilisation of macrophages (Leo et al. 1998, and Richards et al. 1999).

When respiration is inhibited energy ceases to flow, or its flow slows and stagnates, this inhibited flow leads to weakening of the morphogenetic fields, structural disruption, inflammation, swelling, and in more extreme cases cancer and tissue atrophy/death. Many pesticides interfere with mitochondrial metabolism, these pesticides have been linked to neural tube defects (Rull et al. 2006), TCDD (a dioxin) a known carcinogen induces mitochondrial dysfunction, triggering calcium uptake by the cell, and increased ROS, cells became more invasive (Biswas et al.2008). Altered mitochondrial bioenergetics have been linked to cancer since Otto Warburg’s observation that cancer was associated with increased rates of aerobic glycolysis, linking this to some sort of loss of structure within the cell, realising that mitochondrial oxidation involved a greater degree of structure than the simpler fermentation of glycolysis. Recent studies also link mitochondrial function to tumour initiation, invasiveness and regression, with mitochondrial dysfunction producing changes in extracellular matrix modelling (van Waveren et al. 2006). This ability of cancer cells to alter the extracellular matrix supports the idea of a “cancer field” wherein the distorted metabolism of cancer cells generates further distortion in the surrounding tissue, cells bordering on metastases display structural abnormalities (Correa et al. 1998).

Evidence for altered structural properties of cancer cells was found by Raymond Damadian who examined tumour cells with magnetic resonance (NMR) and found increased relaxation times for the water in cancer ells suggesting that it is in a less structured state than water in non-cancer cells, Damadian’s inspiration in examining this was the work of Gilbert Ling (Damadian 1971). Ling’s work has already been mentioned previously on this blog, given the central role of ATP in stabilising the protein-water matrix of the cytoplasm, cancer cells with there characteristic metabolic dysfunction would be expected to show signs of structural disturbance.

Respiration guided by consciousness is the organizing force, when this force is inhibited disease results.

Therapeutics:

The ability to trigger re-differentiation of cancer cells has been virtually ignored by mainstream medicine, but this capacity seems to radically question the idea that cancer is produced by genetic mutations, as the dogma would suggest that if so cancer cells should after mutation be forever determined in their identity.

Given the facts of spontaneous remission and the in vitro inducible cellular re-differentiation of cancer cells into non-cancer cells, as well as the resistance of highly regenerative animals to cancer, an alternative therapeutic approach seems to be possible, instead of the heroic “cut, burn and poison” mode of warfare on the evil mutant cancer monster.

 

“If cancers were werewolves, the cancer industry’s search for more refined killing technologies might be going in the right direction. But the genetic doctrine of cancer’s origin is just as mythical as werewolves and vampires.”

-Ray Peat

Possible practical strategies to take in optimising healing both of injury and cancer would aim at increasing the coherence and strength of the morphogenetic fields, much of this has been discussed previously on this blog (and of course in Ray Peat’s work). Restoration of efficient mitochondrial metabolism being paramount in assisting in differentiation.

Therapeutics would include; meditation to increase conscious inhabitation of our nervous system, promoting a further development of the nervous system, which should increase the trophic morphogenetic aspect of nerve function. Reduced breathing practices such as pranayama and Buteyko technique, to increase carbon dioxide and efficiency of oxygen utilisation. There is also evidence suggestive of a role of carbon dioxide in regenerative processes, it protects the lungs prophylactically from endotoxin induced injury and appears therapeutic post injury (Laffey et al. 2004). Carbon dioxide inhibits lactate formation (Cohen et al. 1990), and appears to shift the cell towards a more “oxidized” state with increased NAD+/NADH ratio (Gyulai et al.1982), cancer cell typically appear more “reduced” favouring NADH (Pelicano et al. 2006). Further carbon dioxide interacts with collagen increasing its ability to structure water, this likely also means the collagen becomes a more coherent communicator, allowing for effective morphogenetic signalling (Specchio et al. 1988). This evidence strongly supports the view of carbon dioxide as a doping agent / cardinal adsorbent / kosmotrope that increases our charge, conductivity and coherence.

Dietary avoidance of anti-metabolic substances would also be useful, these include polyunsaturated fatty acids (vegetable oils, most nuts and seeds and fish oil), inflammatory amino acids such as cysteine, methionine, and tryptophan, found in muscle meats, the typical cuts of meat usually eaten in western diets. Certain food contaminants common in processed foods such as carragenaan should also be avoided.

Supplemental use of adaptogenic herbs, and possible careful use of hormonal treatments such as thyroid, as experimentally induced hyper-thyroidism appears to be able to speed healing and regeneration of neurons (McIsaac and Kiernan 1975 and Lewin-Kowalik et al. 1993), and thyroid hormone speeding wound healing (Safer et al.2005). Neurosteroids such as pregnenolone, progesterone and DHEA due to their generally stabilising effects both on nerve and other cells might also be useful.

References

Becker RO, (1960), The Bioelectric Field Pattern in the Salamander and Its Simulation by an Electronic Analog, Medical Electronics, 7(3), pp. 202-207.

Becker RO, and Spadaro JA, (1972), Electrical stimulation of partial limb regeneration in mammals, Bull N Y Acad Med, 48(4), pp. 627-641.

Biswas G, Srinivasan S, Anandatheerthavarda HK, and Avadhani NG, (2008), Dioxin-mediated tumor progression through activation of mitochondria-to-nucleus stress signalling, PNAS, 105(1), pp. 186-191.

Borgens RB, Vanable JW Jr, and Jaffe LF, (1979), Bioelectricity and Regeneration, Bioscience, 29(8), pp. 468-474.

Borisov AB, Huang S, Carlson BM, (2000), Remodeling of the vascular bed and progressive loss of capillaries in denervated skeletal muscle, The Anatomical Record, 258(3), pp. 292-304.

Carpenter S, and Karpati G, (2004), Necrosis of capillaries in denervation atrophy of human skeletal muscle, Muscle and Nerve, 5(3), pp. 250-254.

Cohen Y, Chang L-H, Litt L, Kim F, Severinghaus JW, Weinstein PR, Davis RL, Germano I, James TL, (1990), Stability of Brain Intracellular Lactate and 31P-Metabolite Levels at reduced intracellular pH during prolonged hypercapnia in rats, J Cereb Blood Flow Metab, 10(2), pp 277-284.

Correa ME, Finol HJ, Marquez A, Sosa L, and Diaz NL, (1998), Ultrastructure of hepatocyte abnormalities in perimetastatic areas, J Submicrosc Cytol Pathol, 30(3), pp. 371-377.

Damadian, R. (1971), Tumor detection by nuclear magnetic resonance, Science, 171, pp. 1151–1153.

Erin N, Boyer PJ, Bonneau RH, Clawson GA, and Welch DR, (2004), Capsaicin-mediated Denervation of Sensory Neurons Promotes Mammary Tumor Metastasis to Lung and Heart, Anticancer Research, 24, pp. 1003-1010.

De Morais OO, Melo DA, Shinzato DH, Silva JM, (2008), Chronic effects of autonomic extrinsic denervation on mast cells number in mesenteric tissue of Wistar rats, Neurobiologia, 71(3), pp. 51-58.

Godwin JW, Pinto AR, and Rosenthal NA, (2013), Macrophages are required for adult salamander limb regeneration, PNAS, www.pnas.org/cgi/doi/10.1073/pnas.1300290110

Gouin J-P, Kiecolt-Glaser JK, and Glaser R, (2008), The Influence of Anger Expression on Wound Healing, Brain Behav Immun, 22(5), pp. 699-708.

Green J, Cairns BJ, Casabonne D, Wright FL, Reeves G, and Beral V, (2011), Height and cancer incidence in the Million Women Study: prospective cohort, and meta-analysis of prospective studies of height and total cancer risk, Lancet Oncology, 12(8), pp. 785-794.

Gyulai L, Dora E, and Kovach AG, (1982), NAD/NADH: redox state changes on cat brain cortex during stimulation and hypercapnia, Am J Physiol, 243(4), pp. 619-627.

Kaminishi M, Shimizu N, Shiomoyama S, Yamaguchi H, Ogawa T, Sakai S, Kuramoto S, Oohara T, (1995), Etiology of gastric remnant cancer with special reference to the effects of denervation of the gastric mucosa, Cancer, 75(1), pp. 1490-1496.

Karpati G, Klassen G, Tanser P, (1979), The effects of partial chronic denervation on forearm metabolism, Can J Neurol Sci, 6(2), pp. 105-112.

Krause S, Maffini MV, Soto AM, and Sonnenschein C, (2010), The microenvironment determines the breast cancer cells’ phenotype: organization of MCF7 cells in 3D cultures, BMC Cancer, 10.

Kulesa PM, Kasemeier-Kulesa JC, Teddy JM, Margarayan NV, Seftor EA, Seftor REB, Hendrix MJC, (2006), Reprogramming metastatic melanoma cells to assume a neural crest cell-like phenotype in an embryonic microenvironment, PNAS, 103(10), pp. 3752-3757.

Kurabuchi S, (1992), Relationship between innervation and forelimb regenerative capacity in the postmetamorphic pond frog Rana brevipoda porosa, Int. J. Dev. Biol, 36, pp. 429-433.

Laffey JG, Honan D, Hopkins N, Hyvelin J-M, Boylan JF, and McLoughlin P, (2004), Hypercapnic Acidosis Attenuates Endotoxin-induced Acute Lung Injury, American Journal of Respiratory and Critical Care Medicine, 169(1), pp. 46-56.

Leo NA, Callahan TA, Bonneau RH, (1998), Peripheral Sympathetic Denervation Alters Both the Primary and Memory Cellular Immune Responses to Herpes simplex Virus Infection, Neuroimmunomodulation, 5(1-2), pp. 22-35.

Lewin-Kowalik J, Koksanowicz E, Barski J-J, Krause M, Gorka D, Golka B, Kwiek S, (1993), Experimental hyperthyroidism enhances the regeneration of central neurites promoted by peripheral nerve grafts in the hippocampus, Restorative Neurology and Neuroscience, 6(1), pp. 57-63.

McCaig CD, and Rajnicek AM, (1991), Electrical fields, nerve growth and nerve regeneration, Experimental Physiology, 76, pp. 473-494.

McIsaac G, and Kiernan JA, (1975), Accelerated recovery from peripheral nerve injury in experimental hyperthyroidism, Experimental Neurology, 48(1), pp. 88-94.

Miledi R, and Slater CR, (1968), Some mitochondrial changes in denervated muscle, J. Cell Sci, 3, pp. 49-54.

Mintz B, and Illmensee K, (1975), Normal genetically mosaic mice produced from malignant teratocarcinoma cells, PNAS, 72(9), pp. 3585-3589.

Muller FL, Song W, Jang YC, Liu Y, Sabia M, Richardson A, Van Remmen H, (2007), Denervation-induced skeletal muscle atrophy is associated with increased mitochondrial ROS production, AJP, 293(3), pp. 1159-1168.

Oviedo NJ, and Beane WS, (2009), Regeneration: the origin of cancer or a possible cure? Semin Cell Dev Biol, 20(5), pp 557-564.

Perez-De-Albeniz A, and Holmes J, (2000), Meditation: concepts, effects and uses in therapy, International Journal of Psychotherapy, 5(1), pp.49-59.

Vandenberg LN, Adams DS, and Levin M, (2012), Normalized shape and location of perturbed craniofacial structures in the Xenopus tadpole reveal an innate ability to achieve correct morphology, Developmental Dynamics, 241(5), pp. 863-878.

Van Waveren C, Sun Y, Cheung HS, and Moraes CT, (2006), Oxidative phosphorylation dysfunction modulates expression of extracellular matrix—remodeling genes and invasion, Carcinogenesis, 27(3), pp. 409-418.

Warburg O, (1956), On the Origin of Cancer Cells, Science, 123(3191), pp. 309-314.

Wicks KL, and Hood DA, (1991), Mitochondrial adaptations in denervated muscle: relationship to muscle performance, Am J Physiol Cell Physiol, 260(4), pp. 841-850.

Pelicano H, Xu R, Du M, Feng L, Sasaki R, Carew JS, Hu Y, Ramdas L, Hu L, Keating MJ, Zhang W, Plunkett W, Huang P, (2006), Mitochondrial respiration defects in cancer cells cause activation of Akt survival pathway through a redox-mediated mechanism, JCB, 175(6), p 913.

Redd MJ, Cooper L, Wood W, Stramer B, and Martin P, (2004), Wound healing and inflammation: embryos reveal the way to perfect repair, Phil. Trans. R. Soc. Lond. B, 359, pp. 777-784.

Richards AM, Floyd DC, Terenghi G, and McGrouther DA, (1999), Cellular changes in denervated tissue during wound healing in a rat model, British Journal of Dermatology, 140(6), pp. 1093-1099.

Rull RP, Ritz B, and Shaw GM, (2006), Neural Tube Defects and Maternal Residential Proximity to Agricultural Pesticide Applications, Am J Epidemiol, 163(8), pp. 743-753.

Safer JD, Crawford TM, and Holick MF, (2005), Topical Thyroid Hormone Accelerates Wound Healing in Mice, Endocrinology, 146(10), pp. 4425-4430.

Singer M, (1952), The influence of the nerve in regeneration of the amphibian extremity, Quarterly Review of Biology, 27(2), pp. 169-200.

Specchio JJ, Karmas E, Daun H, Paik S, and Gilbert SG, (1988), Effect of Carbon Dioxide on the Thermodynamic State of Water in Collagen, Journal of Food Science, 53(4), pp. 1212-1215.

Yan X, Han J, Zhang Z, Wang J, Cheng Q, Gao K, Ni Y, and Wang Y, (2009), Lung cancer A549 cells migrate directionally in DC electric fields with polarized and activated EGFRs, Bioelectromagnetics, 30(1), pp. 29-35.

Axolotl photo: Tim Flach http://www.timflach.com/

Generative Energy Podcast Episode Four: membrane pumps vs. living protoplasm

I talk with Danny Roddy about theories of cell physiology, mechanical membrane pumps vs.  living bioenergetic protoplasm (Gilbert Ling’s A-I hypothesis).

Generative Energy Podcast Episode Four (Special Guest: Phil From Pranarupa) — The Danny Roddy Weblog.

Ontogeny anticipates phylogeny: Evolution, meditation, and the brain.

neotony

“In evolution, the tendency toward dominance of the head (cephalization) in animals overlaps with another tendency (known in plants too) called juvenilization, pedomorphism, or neoteny, in which an early stage of the organism’s development, the juvenile stage is preserved for longer periods in the descendants, eventually becoming the normal adult type. Baby apes resemble humans, in body proportions and behaviour, much more than the adult apes do. The infant represents our evolutionary future.”

-Ray Peat

 embryo_comparisons

            People often talk of ontogeny recapitulating phylogeny, where the embryo during its very early stages of development resembles earlier evolutionary forms, Ray Peat suggests that ontogeny anticipates phylogeny, the embryo (and infant) with its high brain-to-body ratio, appears to prioritize cephalization.

chimps

infant chimp, and adult chimp.

In experiments with chick embryos, Zamenhof, opened eggs at a stage when the brain normally would stop growing, and added glycine, which was likely converted to glucose, although it is also possible the glycine acted as an “inhibitory” neurotransmitter, that is, it acted to stabilise the cytoplasm building structure, the chicks developed larger brains. In other experiments progesterone was found to have a similar effect, increasing brain weight (Ahmad and Zamenhof, 1979). Environmental factors can clearly be modified to enhance developmental potentials, we are not victims of genetic determinism. I think Zamenhof’s experiments are suggestive of a high degree of volition in development, the organism senses the possibilities available, and pursues them as far as the environment permits.

Left: above, adult human skull. Below, infant human skull. Right: above adult capuchin monkey skull. Below infant capuchin monkey skull.

Left: above, adult human skull. Below, infant human skull.
Right: above adult capuchin monkey skull. Below infant capuchin monkey skull.

Cephalisation appears to be a clear priority in all organisms when resources permit, all embryological organisms demonstrate a high degree of cephalisation, at least in the early stages. This can be seen in the development of the axiate pattern, one of the fundamental patterns to emerge in developing organisms, within this pattern, which is fundamentally a metabolic gradient, the area of greatest activity is the apical region, the head (Child 1920). This axiate pattern is the anterior-posterior axis that renders the organism in Mae-Wan Ho’s terms a uniaxial liquid crystal.

I suspect that ideas, such as genetic determinism, are capable of acting as misleading signals, stunting development by encouraging a stupid and passive attitude. The current science culture encourages exactly such an attitude, its mechanistic attempts at modelling Life, taught in schools as facts, are psychic toxins.

Evolution is an active participatory process, the more fully we are capable of inhabiting our own nervous systems, the more fully we are capable of participating. When people are taught to believe, that their growth and development is an entirely deterministic process, controlled by genes, if they accept this belief, they have in effect fallen under a curse. A curse that shrinks them, rendering them less alive to the possibilities of Life.

One of the “limbs” of yoga is pratyahara, the withdrawal of the senses, a turning inward of our energy, rather than allowing it to flow out through external sensory distractions. Pratyahara is a prerequisite to meditation. What sort of state would a an organism be in whilst developing in the womb, what would be the orientation of its consciousness? It seems unlikely that it would be subject to many external sensory distractions.

Meditation has been shown in some studies to prododuce brain growth as well as structural changes such as cortical thickening and increased gyrification, the pattern and degree of cortical folding, increased gyrification means an increased surface area of cortical neurons within the same skull volume (Luders et al. 2012). The increased gyrification of the cerebral cortex increased with the number of years spent practicing meditation. Decreased gyrification is associated with mental retardation, and developmental problems. Gyrification also tends to decrease in aging, along with cognitive ability. Multiple other studies show that meditation is associated with increases in size of brain structures, including hippocampus and frontal gray matter (Luders et al. 2009), and generally increased brain connectivity (Luders et al. 2011).

Meditation increases blood flow to the brain as a whole, by around 65%, with bursts of 25-30 seconds increasing flow 100-200% (Hankey 2006). There is evidence that meditation increases sensory acuity, explanations for this usually suggest that this due to increased areas of the cortex being made available for sensory processing, whilst this may be a factor I think another possibility is that the liquid crystalline cytoplasm increases its internal order, giving it increased sensory resolving power.  Meditators also show increased EEG coherence, associated with increased cognitive processing.

Meditation decreases plasma lactate (Perez-De-Albeniz and Holmes 2000), suggesting that it is acting to increase the efficiency of metabolism, likely through increasing the coherence of the liquid crystalline cytoplasm. Given that mediation is typically accompanied by reduction in respiratory rate it is likely that increased retention of carbon dioxide is at least one factor in this. In a study examining the effect to which advanced meditative practices were capable of altering metabolism, three Buddhist monks were found to be able to raise their metabolism by 61%, and to lower it down to 64% (Benson et al. 1990).

DHEA, a neurosteroid associated with youth, and believed to contribute to brain development, around 50% of total DHEA is produced by the adrenal glands, a large proportion is also produced within the nervous system. Levels typically decline sharply in late adulthood. DHEA was increased in meditators in comparison with age matched controls (Glaser et al. 1992).

As DHEA is an endogenous metabolite that cannot be patented, research on it is limited. Animal levels of DHEA are much lower than human levels, even the non-human primates produce only around 10% of the amount produced in humans (Celec and Starka 2002). Low levels of DHEA are associated with multiple clinical diseases. DHEA appears to have multiple beneficial actions, suggesting that it is interacting with our physiology in a fairly fundamental way, likely a cardinal adsorbent (see Gilbert Ling’s work) or bioenergetic kosmotrope. DHEA protects the beta cells of the pancreas (Coleman et al. 1982) improves insulin sensitivity (Celec and Starka 2002), inhibits the development of cancer (Schwartz 1979), improves various so-called “auto-immune” diseases, including systemic lupus erythematosus, and rheumatoid arthritis (Celec and Starka 2002). DHEA appears to be neuroprotective, protecting against ischaemic injury, and excitotoxic injury from NMDA (Li et al. 2001), considering that neuronal injury involves glutamate release and resultant calcium uptake by the cell, the ability of DHEA to protect against this appears strongly suggestive of a role as a protoplasmic stabilising cardinal adsorbent.

Supplemental DHEA should be considered cautiously as any inflammation within the body has the potential to trigger the transformation of DHEA into estradiol (Castagnetta et al. 2003), which has opposite effects, generally acting to destabilise the cytoplasm, disrupting coherent energy flow.

Meditation appears likely to increase GABA (Guglietti et al. 2013), and Yoga has been shown to increase GABA (Streeter et al.2010), often classed as an inhibitory neurotransmitter, GABA contributes to relaxation, decreasing anxiety, and can enhance immunity (Abdou et al. 2006).

Meditation clearly appears to be able to increase the overall coherence of nervous system function, in turn optimizing production of endogenous metabolites such as GABA, DHEA, and almost certainly also pregnenolone and progesterone, both neurosteroids, these metabolites assist in stabilising this state of increased coherence. If meditation is capable of producing such changes, is it possible that our culture has gone down an entirely mistaken path, with its obsession with external technological “progress”? Perhaps an entirely different culture is possible, one focused on internal biopsychic development?

Padmasambhava / Guru Rinpoche, AKA the second Buddha. "Aww, isn't he cute!!"

Padmasambhava / Guru Rinpoche, AKA the second Buddha.
“Aww, isn’t he cute!!”

References

Abdou AM, Higashiguchi S, Hoire K, Kim M, Hatta H, Yokogoshi H, (2006), Relaxation and immunity enhancement effects of g-aminobutyric acid (GABA) administration in humans, Biofactors, 26(3), pp. 201-208.

Ahmad G, and Zamenhof S, (1979), The effect of progesterone on brain and body growth of chick embryos, Growth, 43 (1), pp. 58-61.

Ahmad G, and Zamenhof S, (1979), The effects of exogenous nutrients on growth of chick embryo brain, Growth, 43(3), pp. 160-166.

Benson H., Malhotra MS, Goldman RF, Jacobs GD, Hopkins PJ, (1990), Three case reports of the metabolic and electroencephalographic changes during advanced Buddhist meditation techniques, Behavioural Medicine, 16(2), pp. 90-95.

Castagnetta LA, Carruba G, Granata OM, Stefano R, Miele M, Schmidt M, Cutolo M, Straub RH, (2003), Increased estrogen formation and estrogen to androgen ratio in synovial fluid of patients with rheumatoid arthritis, Journal of Rheumatology, 30(12), pp. 2597-2605.

Celec P, and Starka L, (2002), Dehydroepiandrosterone-Is the Fountain of Youth Drying Out?  Physiol. Res. 52, pp. 397-407.

Child CM, (1920), Some considerations concerning the nature and origin of physiological gradients, Biological Bulletin, XXXIX (3), pp.147-187.

Coleman DL, Leiter EH, and Schwizer RW, (1982), Therapeutic effects of dehydroepiandrosterone (DHEA) in diabetic mice, Diabetes, 31, pp. 830-833.

Glaser JL, Brind JL, Vogelman JH, Eisner MJ, Dillbeck MC, Wallce RK, Chopra D, Orenteich N, (1992), Elevated serum dehydroepiandrosterone sulfate levels in practitioners of the Transcendental Meditation (TM) and TM-Sidhi programs, Journal of Behavioural Medicine, 15(4), pp. 327-341.

Guglietti CL, Daskalakis ZJ, Radh N, Fitzgerald PB, Ritvo P, (2013), Meditation-related increases in GABAB modulated cortical inhibition, Brain Stimulation, 6(3), pp. 397-402.

Li H, Klein GM, Sun P, Buchan AM, (2001), Dehydroepiandrosterone (DHEA) reduces neuronal injury in a rat model of global cerebral ischemia, Brain Research, 888, pp. 263-266.

Luders  E, Kurth F, Mayer EA, Toga AW, Narr KL, and Gaser C, (2012), The unique brain anatomy of meditation practitioners: alterations in cortical gyrification, Frontiers in Neuroscience, 6, 34.

Luders E, Clark K, and Toga AW, (2011), Enhanced Brain Connectivity in Long-term Meditation practitioners, Neuroimage, 57(4), pp. 1308-1316.

Luders E, Toga AW, Lepore N, and Gaser C, (2009), The underlying anatomical correlates of long-term meditation: larger hippocampal and frontal volumes of gray matter, Neuroimage, 45(3), pp. 672-678.

Peat R (1976), Mind and Tissue: Russian Research Perspectives on the Human Brain.

Peat R, (1994), Generative Energy: Restoring the Wholeness of Life.

Perez-De-Albeniz A, and Holmes J, (2000), Meditation: concepts, effects and uses in therapy, International Journal of Psychotherapy, 5(1), pp.49-59.

Schwartz AG, (1979), Inhibition of Spontaneous Breast Cancer Formation in Female C3H (Avy/a) Mice by Long-TermTreatment with Dehydroepiandrosterone, Cancer Research, 39, pp. 1129-1132.

Streeter CC, Whitfield TH, and Jensen JE, (2010), Effects of Yoga Versus Walking on Mood, Anxiety, and Brain GABA Levels: A Randomized Controlled MRS Study, J Altern Complement Med, 16(11), pp. 1145-1152.

Generative Energy: Viktor Schauberger, Ray Peat, Biomagnetic oxidative metabolism, implosion and evolution.

“In every case do the opposite to whatever technology does today. Then you will always be on the right track.”

 

“They called me deranged. The hope is that they are right. It is of no greater import if another fool wander this Earth. But if I am right and the science is wrong – then may the Lord God have mercy on mankind.”

-Viktor Schauberger

First a disclaimer: My own understanding of Viktor Schauberger’s work is incomplete at best, I have no idea what Ray Peat thinks about Schauberger’s ideas, though I suspect he’s knows of Viktor’s work. What follows are my own musings. If anyone feels I’m misunderstanding Schauberger (or Peat) feel free to let me know. Oh and things might get just a little kooky… you have been warned.

Viktor Schauberger (1885 -1958) was an Austrian Forester, with a deep connection to Nature’s energies. He deliberately avoided higher education seeing the stupefying effect it had on his older brothers, he chose instead to stay in his beloved forests and learn direct from Nature.

Viktor Schauberger

Viktor Schauberger

Much of his writing can seem somewhat mystical, Schauberger lacked formal scientific training and developed much of his own terminology such as “ethericities”, “qualigens”, “fructigens”, and “dynagens” as well as using scientific terminology in ways that do not entirely agree with their traditional uses in science (Schauberger’s use of magnetism and electricism seems a little different from their standard definitions), given this his work is not the easiest to understand, but I am convinced he was describing to the best of his ability real energetic processes, that he actually experienced.

Schauberger was ahead of his time in viewing the earth as a living, developing organism, his main work focuses on the importance of water within the biosphere (sounds obvious right, but wait), and the centrality forests in mediating the flow of water, as they are both enlivened by it, protect it, and generate it, further a healthy flow of water could Viktor claimed grow, living water itself generated new water, this of course is counter to the dead mechanistic worldview of conventional science, and judging from the results that that science has had on this planet I think its safe to say it is a dead end, utterly stupid and dangerously incompetent.

Viktor spent much time observing the flow of water in the high mountain streams of the then still natural, living, old growth forests of Austria, and a number of apparently chance events led to his developing a radically different understanding of the nature of water, and the importance of water and its energies in life.

One day in the middle of a cold winter, when about to cross a fast flowing mountain stream he flushed a stationary trout from its lair, it flashed upstream with incredible speed and apparent ease, Viktor questioned how this was possible, first the spot was cut off downstream by a 60 metre high waterfall, where the water vapourised into mist, how had the trout been holding its position in the torrential waters, near motionless with only the slightest movements of its tail fins, how did it shoot upstream with such ease? How had it surmounted the waterfall?

Later another incident occurred, while out hunting on a cold December morning Viktor found himself in ravine, and noticed heavy logs dancing in an icy stream, he became entranced by the logs watching them for some time until he noticed another unusual phenomenon, rocks, some about the size of a human head, worn by the water into smooth egg shapes began to join the strange dance of the logs, the rocks gyrated upwards, surfacing and as they surfaced they were encircled by a ruff of ice. Whilst these smooth rocks seemed to defy gravity, Viktor noticed that other rough rocks sat motionless on the stream bed. Viktor realised that there must be an explanation for what he had seen, one based on the principles of Nature, even if it lay outside of conventional science.

From such observations Viktor came to understand the way energy moved through nature, he also realised that the type of movement favoured by nature was diametrically opposed to the way energy was moved via the lunatic mechanistic science. In nature a centripetal, inwinding, implosive, pressure and friction reducing radial to axial movement is favoured, in contrast the technologies of “civilisation” favour a centrifugal, outwinding, explosive, pressure and friction increasing axial to radial movement.

Screen shot 2013-02-26 at 20.57.06

Living Energies (Coats C, 2001).

According to Schauberger much of our present technology is a dangerous error, that is ultimately tearing down the highly developed structures of life that have been built up over the course of evolution, internal combustion engines burn up the hydrocarbon “fossil fuels” generated by the living planet, nuclear reactors and weaponry tear apart atoms, ionizing radiation disrupts the finely ordered structures of the “Living state”. If I’m understanding Schauberger correctly these technologies are also in effect fracturing and traumatising the ether, they sound like they are at least, just listen to sound of an internal combustion engine.

For Schauberger water was a living substance, and when in a state of health and vitality one that moved centripetally, continually seeking its ideal body temperature of 4°C, its anomaly point at which it is densest.

The energetics of water are intimately tied to the structures it creates for itself to flow through, contrast the sinuous organic forms of natural watercourses, with the channelized straight banks of rivers murdered through the stupid engineering practices of mechanically minded morons, who believe that Nature is blind, dead, stumbling randomly and aimlessly. Treating water in such a way turns it from a joyous living entity into a rotting, putrefying corpse.

From his understanding of the energetics of water Schauberger developed a number of inventions. For example a log flume Viktor designed, which was predicted to fail miserably by the then authorities on hydrology, performed as Viktor claimed it would, unfortunately Viktor had not taken into account the greed and short sightedness of his employers, a large area of forest was clear felled.

In 1952 a study of Viktor’s theories of hydrodynamics took place, using a range of pipes, varying from standard straight cylindrical pipes, to rifled cylinders, and spiral whorl pipes. In the standard pipes friction steadily increased. Using the spiral whorl pipes, the water flowed as predicted by Viktor and at a number of points a negative resistance to flow / negative friction was measured. This was possible because the energy / character of the water was in harmony with the form of the pipe.

Viktor also created a number of over-unity devices based on the vortical energies he observed, these examples of “eco-technology” avoided in their design the use of straight lines, and simple circles/ cylinders, instead making use of organic sinusoidal, spiral, and ovoid forms, based on Viktor’s maxim, “comprehend and copy nature”. An American consortium became interested in his work and flew Viktor over to the US, Viktor grew suspicious of the group’s motives and it seems nothing came of the project.

This Schauberger dude sounds pretty crazy, what the DHA does this have to do with Ray Peat, there’s been no mention of ice cream, gelatin, or sombreros, what’s up?

If you’ve read much of Ray’s work you’ve probably come across a few references to V.I. Vernadsky, and in particular the idea of viewing the organism as a “whirlwind of atoms”.

“The moving air in a whirlwind forms a self-intensifying system, with the motion reducing the pressure, causing more air to be drawn into the system. The atoms moving in coordination aren’t acting as separate things, but as parts in a larger thing. The way in which increased metabolism in the bones acts favorably on the metabolism of kidneys, blood vessels, lungs, liver, digestive system, etc., which in turn favors the bones’ renewal, is analogous to the tendency of a whirlwind to intensify as long as there is a source of energy. The intensity of oxidative metabolism is the basic factor that permits continuing coordination of activity, and the harmonious renewal of all the components of the organism.

This view of efficient oxidative metabolism acting like a pressure reducing whirlwind, drawing ever more energy into the system fits with Schauberger’s emphasis on the centripetal energetic movement as the structure generating, and quality increasing “biological vacuum”. Viktor claimed that this state of centripetally flowing energy led to the phenomenon he called biomagnetism, a levitational evolutionary force.

Agents which inhibit the efficient inflow of energy can all be seen in Schauberger’s model as acting centrifugally, increasing pressure, inhibiting the influx of energy, leading to the dedifferentiation of highly individuated energy structures. Chaotropic agents such as ionizing radiation, estrogen, endotoxin and serotonin all act in such a manner, stimulating water uptake by the cell, inhibiting mitochondrial metabolism and generally causing inflammation, these effects could all be characterized in Schauberger’s scheme as centrifugal / explosive, the cell swells / inflames taking up water, this water is in a chaotic less structured state, having a higher structural temperature as if it has been heated. Further Viktor realized that this explosive energetic movement was carcinogenic leading to cancerous growths in plants and animals, resulting from the stagnation/distortion of energy flow, and the decrease in dynamic order, “cancer is an entity that has been expelled from a state of order”. Viktor associated this centrifugal energy and its increase in pressure with what he termed “electricism”, which impeded evolution, resulting in stagnation and degeneration.

One observation Viktor made in relation to this, was that what was called “light induced growth”, the phenomenon of larger annual rings in light barked trees when exposed to strong sunlight, was in fact a precancerous condition predisposing the tree to disease. The idiots able only to conceive of the world in terms of quantity could not perceive the decrease in quality, Viktor realized that the optimum environment for such light barked trees was the depths of the forest shielded from overexposure to sunlight, attempts to turn forests into wood farms / factories would produce not only poor quality wood, but ultimately lead to the degeneration of the forest, as the chaotropic influence spread. Viktor could see the forest as complex living organism, where diversity and cooperation was the rule, uniformity is contrary to Nature. The environmental degeneration caused by deforestation and monocultural forest factories spreads because the insuctional metabolic energies of the trees degenerates, and the water cycle is disrupted, Life is a transmutative flow of energy, when this flow is interfered with at one point it is capable of distorting the whole.

All things into one are woven, each in each doth act and dwell.”  (Goethe).

The wholeness of life can be restored.

If energy can be caused to move inappropriately, then it should also be possible to restore the Natural, evolutionary flow.

Within our physiology those agents such as progesterone and carbon dioxide that oppose the chaotropes, support mitochondrial metabolism favouring the centripetal “biomagnetic” energy influx, being able to powerfully correct distortions in the energy structure. Viktor observed that when water was flowing centripetally it was self-purifying capable of breaking down / transforming toxins and pathogens, and of course a healthy metabolism is capable of great resistance to toxins especially if aided by catatoxic agents such as progesterone.

You what? What is this gibberish, it almost sounds like you’re saying mitochondria are generating electromagnetic vortices?

Pretty much, yes, I think what may be happening is that mitochondria, or the flow of energy through them is doing just that, creating electromagnetic in-winding vortices that emulsify the various “substances” that compose us, and when unimpeded by de-cohering influences acts as a self-intensifying system allowing for individuation / evolution. These in-winding energetic vortices guide the flowing liquid crystalline structures that in turn assist in the inflow of greater energy. These energetic vortices can be seen in the “metabolic gradients” that CM Child (1920) saw as fundamental determinants of pattern formation, playing key roles in organismic development and regeneration. Child noticed that in the development of the axiate pattern, the apical region (the head) was the area of greatest metabolic activity.The following time-lapse video shows the role such bio-electric effects play in morphogenesis, in this case the bio-electric outline of the face of an embryonic tadpole:

The flowing “biomagnetic” state of Schauberger’s model seems to fit with the way in which Ray Peat understands efficient oxidative metabolism as functioning. Further when this efficient oxidative metabolism is inhibited it tends to result in an overly reduced, electronically excited state that may correlate with what Schauberger terms “electricism”, this electronically excited state also inhibits oxidative metabolism. The Living-state for Szent-Gyorgyi (1977) was the electronically desaturated state, that allows for the development of increasingly complex life. Szent-Gyorgyi argues that cancer results from a failure in electronic desaturation, leading to loss of differentiated structure (Pohl et al. 1977). Ionizing radiation exerts its effects on organisms through electrical excitation, interfering with the dynamically ordered flowing fields of the organism. Estrogen synergizes with radiation, both appear to act in similar ways on the organism, progesterone protects against both (Segaloff 1973).

Respiration is clearly involved in the generation of energetic field effects, the greater the intensity of respiration the greater the field strength, tumors appear to arise from distortions of this flowing field, their own disordered metabolism then becomes a self reinforcing system, generating a tumor field. This view of cancer as fundamentally a disorder of the individuating fields is hardly ground breaking, it has been suggested by many others including Joseph Needham (1936), the solutions to this disorder are relatively simple, although somewhat lacking in profit-making potential.

Viktor claimed that the centripetal energetic motion effectively bound and emulsified oxygen, using it for increasing qualitative transformation, when this movement was inhibited Viktor claimed that oxygen could become excessively reactive and aggressive, carbon dioxide which appears to “grease the pathways” of oxidative metabolism decreases reactive oxygen species (ROS) and lipid peroxidation, Schauberger talks about “carbones” (kohle-stoffe), which he saw as “mother substances” acting to safely emulsify oxygen whilst they were in turn fertilized by it.

This model of seeing the organism as a complex flowing emulsion generated by in-winding electromagnetic vortices seems consistent with ideas such as the rLung (psychic winds) of Vajrayana Buddhism, and the Prana vayus of Yoga. The chakras also can be conceived as electromagnetic vortices closely associated with various endocrine glands.

Whilst systems such as Yoga have traditionally focused on generating connected, coherent, unified individuals, Schauberger was looking primarily at the environment as a whole, he was incredibly critical of much of human activity but also realized that we undoubtedly had a role to play on this planet, if we can collectively get our acts together. Viktor believed that conscious, energetically connected and sensitive human becomings, could and were intended to help birth a higher, more qualitatively developed planetary biosphere, this seems to have much in common with the emergent evolution of Vernadsky’s Noosphere. Of course yet again a view of Life as purposeful is found here, and it is directly opposed to the blind idiot view of life as a random meaningless event, where we can pillage a world of dead matter, that somehow managed to jumble together the molecular ‘mechanisms’ that produce human life.

If Schauberger is correct and such a planetary evolution is possible, then all of our efforts should be dedicated to this for no other project can mean so much. A scientific paradigm shift will be required, one that can see and accept a Living, bio-energetic Universe, the current “science” (more accurately a nescience) with its ideology of randomness, and mechanistic mindset, viewing us as “lumbering robots” piloted by “selfish genes”, is a blight on Life. The biosphere, in particular the remaining forests must be protected. Those who can still see that this world is a living, developing organism, should be supported. Reforestation programs would seem to be necessary, rivers and the natural flow of water must be encouraged, the current hydroengineering of rivers, through channelization and dams needs to be reconsidered. Our technology and its power source will need to radically change, nuclear power must be eliminated from this planet. This does not mean necessarily a civilization completely lacking in technology, but one whose technology is in harmony with Nature, eco-technology.

Ok, that’s it you’re insane, even if something like that could happen, it’s an impossible task!

Yeah, seems that way, though for some reason all I can think to say is,

“Go beyond the impossible, and kick reason to the curb!!!!!”

 

 

 

References

Child CM, (1920), Some considerations concerning the nature and origin of physiological gradients, Biological Bulletin, XXXIX (3), pp.147-187.

Coats C, (2001), Living Energies, Gateway, Dublin.

Needham J, (1936), New advances in the chemistry and biology of organized growth: section of pathology, Proc. R. Soc. Med. 29, pp. 1577-1626.

Peat, R, (1994), Generative Energy.

Peat, R, Osteoporosis, aging, tissue renewal, and product science, http://raypeat.com/articles/articles/osteoporosis-aging.shtml

Pohl HA, Gascoyne PR, and Szent-Gyorgyi A, (1977), Electron spin resonance absorption of tissue constituents, PNAS, 74(4), pp. 1558-1560.

Schauberger V, The Water Wizard, translated and edited by Coats, C, Gateway, Dublin.

Schauberger, V, Nature as Teacher, translated and edited by Coats, C, Gateway, Dublin.

Schauberger, V, The Fertile Earth, translated and edited by Coats, C, Gateway, Dublin.

Schauberger V, The Energy Evolution, translated and edited by Coats, C, Gateway, Dublin.

Segaloff A, (1973), Inhibition by progesterone of radiation-estrogen-induced mammary cancer in the rat, Cancer Res, 33, pp. 1136-1137.

Szent-Gyorgyi A, (1977), The Living-State and Cancer, Biophysics, 74(7), pp. 284-2847.

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